Insights Into the Selective Imprinted Polymer of Voriconazole from Host-Guest Interaction Perspective

The incidence of fungal coinfections, such as Aspergillus spp., in patients with COVID-19 has been widely reported. Voriconazole is the first-line treatment for aspergillosis. A challenging sample preparation process is required to perform therapeutic drug monitoring of voriconazole. Recently, Molecularly Imprinted Polymers (MIP) have been shown to improve the separation selectivity for biological samples. Monomer selection in MIP is often performed by trial and error, without a design strategy. Therefore, this study aimed to construct a high-affinity MIP for voriconazole based on its interaction with functional monomers. All structures were optimized with B3LYP/6-311G++(d,p) and DFT-D3 dispersion correction method. Calculations of vacuum and solvated frequencies were carried out using a structure with maximum binding energy from molecular docking. The results showed that complex five was the most stable, exothermic, spontaneous, and enthalpy-driven among the complexes. In addition, there are nine intermolecular interactions and one moderate hydrogen bond in the QTAIM and NBO analysis, whereas hydrogen bonds, van der Waals interactions, and hydrophobic interactions were observed in the NCI-RDG analysis. The findings of this preliminary investigation showed that voriconazole possesses high stability when combined with functional monomers. It also provides information and assistance for further laboratory MIP synthesis.

Overtourism in Indonesia after the COVID-19 Pandemic: Social Psychology Perspective

La industria del turismo sufrió una pérdida significativa por la pandemia de COVID-19. Sin embargo, en línea con la disminución de los impactos de COVID-19, el comportamiento turístico reciente puede ser la causa de un fenómeno llamado sobreturismo. El objetivo de este estudio fue investigar los fenómenos únicos del sobreturismo en Indonesia después de la pandemia de COVID-19 a través de un enfoque psicológico social. Mediante un análisis crítico del discurso, este estudio encuentra que una emoción negativa generada por la pandemia de COVID-19 ha llevado al "turismo de venganza" provocado por dos años de aislamiento. Después de que el efecto de transmisión de COVID-19 está disminuyendo, las personas que experimentan un colapso psicológico ventilan sus intereses turísticos simultáneamente, lo que a su vez provoca un exceso de turismo. Desde la perspectiva de la psicología, la emoción negativa acumulada durante el confinamiento puede ser la razón del exceso de turismo. Mientras tanto, el exceso de turismo también tiene un impacto social negativo. Desde la perspectiva de la psicología social, el apego al lugar es una de las necesidades básicas de todo ser humano. Cuando se interrumpe el control sobre su entorno, esto puede generar muchos problemas. El exceso de turismo descontrolado provoca daños ambientales y reduce la calidad del turismo. Por lo tanto, este estudio sugiere que el gobierno y las partes interesadas colaboren para mitigar los desastres turísticos para prevenir la amenaza del turismo excesivo a la sostenibilidad del turismo.Alternate abstract:The tourism industry suffered a significant loss from the COVID-19 pandemic. However, in line with decreasing the COVID-19 impacts, recent tourism behavior may be the cause of a phenomenon called as overtourism. The aim of this study was to investigate the unique phenomena of overtourism in Indonesia after the COVID-19 pandemic through a social pyschological approach. By using a critical discourse analysis, this study finds that a negative emotion generated by the COVID-19 pandemic has led to "revenge tourism" caused by two years of isolation. After the transmission effect of COVID-19 is decreasing, people who experience psychological breakdown, vent their tourism interests simultaneously, which in turn causing overtourism. In the perspective of psychology, negative emotion that has been piled up during lockdown may be the reason of overtourism. Meanwhile, overtourism also has negative social impact. From social-psychology perspective, place attachment is one of the basic needs in all human. When the control over their environment was disrupted, this may lead to many problems. Uncontrolled overtourism causes environmental damage and reducing the quality of tourism. Thus, this study suggests that the government and stakeholders collaborate to mitigate tourism disasters to prevent the threat of overtourism to tourism sustainability.

The Influence of Interactive Digital Worksheets Based on Level of Inquiry Towards Science Process Skills in Elementary School

The challenge of learning science during the COVID-19 pandemic in elementary schools focuses on the need for digital learning materials for Science Process Skills (SPS) through the perspective of science as an investigation process. This study aims to investigate the influence of interactive digital worksheets based on level of inquiry towards science process skills during the covid-19 pandemic in elementary school. In the study a quasi-experimental research design with pretest-posttest control groups was adopted. The participants were composed of 124 fifth grade elementary school students. The data were collected via the SPS test through measurement indicators of observation, classifying, communication, measuring, inference, and prediction aspects. The obtained data were analyzed using independent sample t-test after going through the assumption test of normality, homogeneity and balance. The results of calculating the hypothesis test obtained p = 0.000 at a significance level of 5% indicating that there is a difference between IDW and student SPS. The effect size test was obtained by a percentage of 66.18% so that it can be concluded that the use of IDW based on LoI can effectively increase SPS in elementary school students. Interactive facilities and ease of access as well as the suitability of work stages based on the LoI contribute to student independence and stimulate student SPS in elementary schools during learning during the pandemic. © 2022, Pegem Egitim ve Ogretim Dergisi. All Rights Reserved.

The phenomenon of financial distress of manufacturing companies in Indonesia during the Covid-19 Pandemic

The purpose of this study is to examine the differences in the value of the financial distress of manufacturing companies before and after the Covid-19 pandemic, as well as to examine the determinants that affect the financial distress of manufacturing companies before and after the Covid-19 pandemic. This study is a quantitative study with the population in this study namely manufacturing companies in Indonesia. The sample is 1005 Firm Years in manufacturing companies in Indonesia. These Manufacturing Companies were taken from 2016-2021, but we divided the sample into 2 categories, namely 2016-2019, namely in the pre-pandemic period as many as 653 firm years, and during the pandemic as many as 352firm years. The dependent variable used in this study is financial distress, measured by the O-Score Model. Furthermore, the independent variables are profitability using ROA, liquidity using the current ratio, and leverage using the Debt to Assets Ratio. The test results show no difference between the financial distress of manufacturing companies in Indonesia before and during the pandemic. During the pandemic, financial ratios became more considered in predicting financial distress than before the pandemic. The role ofprofitability is a factor that impacts financial distress is more impactful in the pre-pandemic period. The role of liquidity being a factor that impacts financial distress is more impactful during the pandemic. Leverage can also be a good indicator in predicting financial distress both in the pre-pandemic and during the pandemic.

Utilization of Medical Mask Wastes as Filter Material for Air Purification Units

The COVID-19 pandemic significantly increased the amount of infectious medical wastes produced, with medical mask wastes being one of the largest contributors. Present research focuses on trying to turn medical mask waste into a functioning air filter by modifying it with CuO/TiO2 to reduce the amount of infectious medical wastes laying around. Synthesis of CuO/TiO2 was confirmed with FESEM-EDX, UV-Vis DRS and XRD techniques. The optimum amount of Cu added (1%wt of TiO2) was determined by assessing the degradation performance of the modified medical mask wastes against an organic pollutant (methylene blue) and a biological pollutant (S. aureus). The filter was then integrated into a simple air purifying unit and complemented with a UV-C germicidal lamp and a plasma ion generator. The prototype of the simple air purifying unit was able to degrade 100% tobacco smoke in less than 15 min and 30.8% CO gas in 30 min. © 2022 Chemical Publishing Co.. All rights reserved.

Drivers of Stunting Reduction in Yogyakarta, Indonesia: A Case Study.

BACKGROUND: Chronic malnutrition in children is a severe global health concern. In Yogyakarta, the number of children who are too short for their age has dropped dramatically over the past few decades. OBJECTIVE: To perform an analysis of trends, policies, and programs; and an assessment of government, community, household, and individual drivers of the stunting reduction in Yogyakarta, Indonesia. METHOD: Using a mixed-methods approach, there were three types of research: (1) analysis of quantitative data, (2) evaluation of stunting policy, and (3) focus group discussions and in-depth interviews to collect qualitative data. RESULTS: The prevalence of stunting has decreased from year to year. Mean height-for-age z-scores (HAZ) improved by 0.22 SDs from 2013 to 2021. Male and female toddlers aged <20 months have relatively the same body length as the WHO median, but it is lower for children >20 months old. The COVID-19 pandemic has contributed to an increase in stunting-concurrent wasting. Nutrition-specific and -sensitive interventions have been carried out with coverage that continues to increase from year to year, although in 2020, or at the beginning of the COVID-19 pandemic, the coverage of specific interventions decreased. The government has committed to tackling stunting by implementing the five pillars of stunting prevention and the eight convergent stunting actions. As the drivers of stunting reduction, national and community stakeholders and mothers, at the village level, cited a combination of poverty reduction, years of formal education, prevention of early marriage, access to food, enhanced knowledge and perception, and increased access to sanitation and hygiene. CONCLUSIONS: Nutrition-specific and -sensitive sector improvements have been crucial for decreasing stunting in Yogyakarta, particularly in the areas of poverty reduction, food access, preventing child marriage, sanitation, education, and increasing knowledge and perception.

Sentiment Analysis as Assessment of the COVID-19 Social Assistance Pollemic using Random Forest Algorithm

The government's endeavors in organizing the COVID-19 Social Assistance program often encounter problems and lead to the opinion of many parties. One of the opinions expressed on social media is twitter. Sentiments from these opinions were then analyzed to find out the assessment and discussion of each sentiment that can be used as evaluation material for the Social Assistance program. In this study, the sentiment of each preprocessed text was obtained using a labeling process with an assessment of polarity and subjectivity from TextBlob library. The results of neutral, positive, and negative sentiment assessments were weighted using TFIDF. Words that have been formatted into numeric then classified using the Random Forest algorithm. The parameters in this case were in accordance with the documentation on sklearn. An evaluation of the algorithm was also carried out using the 10 kfold cross validation method as a performance validation of the results of testing each piece of data. The performance obtained is quite satisfactory. © 2022 IEEE.

Community response to COVID-19 handling in Namorambe District, Deli Serdang Regency

The spread of the Corona virus or better known as Covid-19 cannot be estimated when it will end. This condition is very concerning, including Indonesia, which has the highest death toll in Southeast Asia. This virus has also spread in North Sumatra including Deli Serdang Regency. One of the biggest challenges in mitigating Covid-19 is building public awareness about the importance of following the Covid-19 protocol in carrying out daily activities. Unfortunately, this condition is exacerbated by the low level of public awareness by ignoring health protocols during the pandemic period. It is hoped that the role of universities in educating the public can help prevent the spread of Covid-19 and increase community participation in mitigating efforts to prevent its spread. One of them is through community service activities by utilizing traditional ingredients for health drinks which are held at the Villa Mutiara Johor II Complex and its surroundings, Kec. Namorame, Deli Serdang Regency.

Can information sharing predict fresh produce supply chain performance amid the COVID-19 pandemic? A social learning perspective

Purpose This research aims to provide a predictive model assessment on the effect of information sharing on fresh produce supply chain (FPSC) performance during the COVID-19 pandemic by incorporating information quality as an important part of information sharing, as well as cognitive and affective appraisals as part of a social learning process (mediators) into the model. Design/methodology/approach An online survey was conducted on 197 small fresh produce (fruits and vegetables) retailers in Indonesia during the COVID-19 pandemic. The data were analysed using Partial Least Squares Structural Equation Modeling (PLS-SEM) particularly PLSpredict supported by SmartPLS 4 software. Findings This research reveals that information sharing is positively and significantly associated with information quality and that the two constructs are not directly associated with FPSC performance. The path analysis suggests that the effect of information sharing on FPSC performance is fully mediated by cognitive and affective appraisals to the information-sharing activity. It also suggests that the effect of information quality on FPSC performance is fully mediated by affective rather than cognitive appraisal. This model shows a high predictive power and highlights the pivotal role of the learning process during the COVID-19 pandemic. Originality/value This research is the first to employ a predictive model assessment in PLS-SEM to empirically predict the effect of information sharing on FPSC performance using a social learning perspective, particularly in the context of the COVID-19 pandemic.

ANALYSIS OF INNOVATION STRATEGIES TO INCREASE THE COMPETITIVE ADVANTAGES OF THE BANGKALAN COASTAL STYLE HAND-DRAWN BATIK INDUSTRY DURING THE COVID-19 PANDEMIC

Bangkalan coastal style hand-drawn batik is a regional leading creative industry that has experienced difficulties in industrial development during the Covid-19 pandemic. Because marketing relies more on direct interaction with buyers, social distancing policies, Large Scale Social Restrictions (or PSBB), and Enforcement of Restrictions on Community Activities (or PPKM) also impacted the decline in sales volume. To survive, innovation strategies are needed to increase competitive advantage. This study aims to analyze the innovation strategy, including product innovation, marketing, technology, and cooperation, to increase competitive advantage. Data were collected through in-depth interviews, observation, and documentation. The results indicate that innovation strategies can increase competitive advantage, and hand-drawn batik SMEs has enormous development potential. Government intervention affects Small and Medium-sized Enterprises (SMEs), in this case, Bangkalan coastal style hand-drawn batik, to be able to carry out various innovations.

Effect of a Short Course on Improving the Cadres' Knowledge in the Context of Reducing Stunting through Home Visits in Yogyakarta, Indonesia.

Background: Stunting is primarily a public health concern in Low- and Middle-Income Countries (LMIC). The involvement of Integrated Health Service Post (Indonesian: Posyandu) cadres is among the strategies to combat stunting in Indonesia. Objective: This study aimed to determine the effect of a short course on cadres' knowledge. Method: A single group pre-test post-test design was conducted in Yogyakarta, Indonesia, from March to May 2022. Thirty cadres were selected based on the following criteria: willingness to participate, the number of stunted children in their Posyandu, able to read and write, and full attendance at the short course. The knowledge scores were measured by a questionnaire using true and false answers after a short course (post-test 1) and 4 weeks later (post-test 2). We apply STATA 16 to calculate the Mean Difference (MD) using a t-test and a Generalized Estimated Equation (GEE). Furthermore, the adequacy of the short course was evaluated with in-depth interviews. Result: GEE analysis showed that after controlling for age, education, occupation, and years of experience, the short course improved cadres' knowledge significantly on post-tests 1 and 2, i.e., knowledge regarding Children Growth Monitoring (CGM) (Beta = 6.07, 95%CI: 5.10-7.03 and Beta = 8.57, 95%CI: 7.60-9.53, respectively), Children Development Monitoring (CDM) (Beta = 6.70, 95%CI: 5.75-7.65 and Beta = 9.27, 95%CI: 8.31-10.22, respectively), and Infant Young Children Feeding (IYCF) (Beta = 5.83, 95%CI: 4.44-7.23 and Beta = 11.7, 95%CI: 10.31-13.09, respectively). Furthermore, the short course increased their self-efficacy, confidence, and ability to assist stunted children through home visits. Conclusion: The short courses consistently and significantly boosted cadres' knowledge of CGM, CDM, and IYCF, and appropriately facilitated cadres in visits to the homes of stunted children's home.

Waste treatment innovation for infusion bottles using soil solution.

The amount of medical waste, especially infusion bottles, is a problem for environmental pollution. Improper management of infusion bottle waste can have an impact on disease transmission. The medical waste treatment used high technology and high costs will be a financial burden, so simple and effective treatment innovations is needed. This study uses an experimental method of removing bacteria from infusion bottles using a mixture of water and Andoso soil as a solution for washing infusion bottle waste. The soil solution concentration used in washing was 45% with a contact time of 2 minutes. The experiment was carried out with two repetitions. The treatment effect on decreasing the number of bacteria using a multiple linear regression mathematical model. The results showed that the disinfection process of bacterial-contaminated infusion bottles using water required rinsing up to six times, whereas using 45% andosol soil solution only rinsed once. The effectiveness of the disinfection of infusion bottles contaminated with bacteria using soil solution reduces the number of bacteria by 98%.

The Indonesian Government Capacity in Responding to the COVID-19 Impacts on the Creative Economy Sector

Extensive research has been carried out on government capacity to cope with the pandemic. However, little study on this issue exists examining it in the context of the creative economy sector. It has been argued that the successful organizations to address changes in the environment are determined by their organizational capacity. In this paper, we analyze the Indonesian government’s capacity to recover the creative economy sector during the first year of the COVID-19 pandemic. The qualitative content analysis method and key informant interviews were undertaken to understand government capacity. The paper extended the RISE (resilience, intention, sustain, and endurance) model to understand the process of government actions in recovering the creative economy sector from the adverse effects of the COVID-19 pandemic. The RISE model portrays the government’s capacity to respond to the hostile and uncertain environment through tax and loan relaxation, social and health assistance, and capacity building. This paper provides valuable insight into public administration by highlighting government responses to the global pandemic. By analyzing four stages of government actions in restoring the creative economy sector, this study shows that the expected outcomes are far from satisfactory. The government intervention during the first year of the COVID-19 pandemic becomes ineffective because the government is weak in preparing the creative economy recovery policies according to the needs of creative economy actors and accurate data. These findings suggest that the central and local government should improve their collaborative capacity to upgrade the creative economy recovery programs according to the local aspiration.

Analysis on Current Management of Covid-19 Infectious Waste from Self-Isolation Patient towards New Habit Adaptation Era in Indonesia: A Case Study of Sumatera Island (preprint)

In preparation for a new habit adaptation era, Covid-19 infectious waste of self-isolation (SI) patient at home may become a concern in Indonesia. Therefore, the current study evaluates the implementation of the infectious waste management of SI patients (households) in Padang, Medan and Banda Aceh City, Sumatera, through online questionnaires and in-depth interviews. SWOT analysis identifies strengths, weaknesses, opportunities, and threats of the current condition for developing strategies and sustainable programs. Despite the national circular letter instructing the management of the Covid-19 infectious waste from SI patients having been issued, waste management is still not implemented properly. It is likely that most of the Covid-19 infectious wastes from SI patients mix with other household waste and move to the municipal landfill. A lack of concern from the government and society could be the main cause. This creates subsequent problems, such as facility and personnel shortages, lack of coordination, poor campaigns, etc., finally resulting in the low awareness and participation of society. The local government could build partnership with a third-party company and seek assistance of national and international institutions. To ensure sustainability, the Indonesian government must establish an integrated monitoring system to evaluate the program implementation at various levels.

Designing multi-epitope based peptide vaccine candidates against SARS-CoV-2 using immunoinformatics approach.

Introduction: The current incidence of the novel coronavirus disease has shown only small reductions of cases and has become a major public health challenge. Development of effective vaccines against the virus is still being encouraged such as multi-epitope vaccines designed from the components of SARS-CoV-2 including its spike, nucleocapsid and ORF1a proteins. Since the addition of adjuvants including HABA protein and L7/L12 ribosomal are considered helpful to increase the effectiveness of the designed vaccine, we proposed to design multiepitope vaccines by two different adjuvants. Methods: We used the IEDB server to predict BCL and TCL epitopes that were characterized using online tools including VaxiJen, AllPred and IL-10 Prediction. The selected epitopes were further constructed into multiepitope vaccines. We also added two different adjuvants to the vaccine components in order to increase the effectiveness of the vaccines. The 3D-structured vaccines were built using trRosetta. They were further docked with different Toll-like-receptors (TLR 3, 4 and 8) and the entry receptor of SARS-CoV-2, ACE2 using ClusPro, PatchDock and refined by FireDock. All structures were visualized by USCF Chimera and PyMOL. Results: In this study, we succeeded in designing two different candidate vaccines by the addition of HABA protein and L7/L12 ribosomal as adjuvants. The two vaccines were almost equally good in terms of their physicochemical properties and characteristics. Likewise, their strong interactions with TLR3 4, 8 and ACE2 show the lowest energy level of both was estimated at more than -1,000. Interactions of vaccines with ACE2 and TLRs are essential for activation of immune responses and production of antibodies. Conclusion: The two designed and constructed multiepitope vaccine have good characteristics and may have the potential to activate humoral and cellular immune responses against SARS-CoV-2. Further research is worth considering to confirm the findings of this study.

Analysis of Indonesian tourism potentials through the sustainable tourism perspective in the new normal era

Artikel ini bertujuan untuk menggambarkan sejauh mana Indonesia dapat keluar dari "belitan" pandemi COVID-19, khususnya di sektor industri pariwisata. Tujuan lain dari penulisan artikel ini adalah untuk menganalisis peran pemerintah Indonesia dalam menggunakan istilah "normal baru" dan kaitannya dengan pariwisata berkelanjutan selama pandemi COVID-19 belum berakhir. Pariwisata saat pandemi COVID-19 menjadi fokus pembahasan artikel ini karena Pariwisata merupakan salah satu industri yang paling dirugikan oleh pandemi COVID-19. Secara global kerugian pariwisata dunia mencapai US $ 22 miliar. Angka ini akan terus meningkat selama pandemi ini tidak dapat dikendalikan melalui vaksin dan obat-obatan. Tak terkecuali Indonesia yang kehilangan pendapatan asli negaranya dari sektor ini mencapai puluhan triliun rupiah hanya dalam waktu empat bulan sejak WHO mengumumkan COVID-19 sebagai pandemi global. Situasi normal baru dalam kondisi pandemi COVID-19 yang masih berlangsung merupakan peluang sekaligus tantangan bagi dunia pariwisata pada umumnya dan pariwisata Indonesia pada khususnya. Perubahan gaya hidup dan kebiasaan masyarakat dalam berwisata secara langsung maupun tidak telah menghantam” sangat keras industri ini, tidak dapat dipungkiri, mengaktifkan kembali kegiatan industri pariwisata memang memiliki resiko yang cukup besar namun di sisi lain banyak sektor industri pariwisata yang bergantung pada kehidupan masyarakat. Strategi Cleanliness, Health, Safety, Environment Sustainability (CHSE) yang dilakukan oleh pemerintah Indonesia merupakan salah satu upaya untuk kembali menggerakkan sektor pariwisata Indonesia di tengah pandemi COVID-19, sekaligus peluang untuk menerapkan tiga prinsip utama pariwisata berkelanjutan di Indonesia. era normal baru, yaitu melibatkan sektor sosial dalam keterlibatan kebijakan, menjaga keberlanjutan sumber daya alam, dan menjadikan pembangunan berkelanjutan sebagai sinonim dari pertumbuhan ekonomi. Kata Kunci: Pariwisata, COVID-19, New Normal, CHSE This article is part of an international relations study conducted by the authors. This study aims to illustrate the extent to which Indonesia can get out of the "entanglement" of the COVID-19 pandemic, especially in the tourism industry sector. Another purpose of writing this article is to analyze the Indonesian government's role in using the term "new normal" and its relation to sustainable tourism during the COVID-19 pandemic has not ended. Tourism during the COVID-19 pandemic is the focus of the discussion of this article because it is one of the industries most harmed by this pandemic. Globally the loss of world tourism reaches US$22 billion. This figure will continue to increase as long as this pandemic cannot be controlled through vaccines and drugs. No exception for Indonesia which lost the country's original income from this sector reaching tens of trillions of rupiah in just four months since WHO announced COVID-19 as a global pandemic. The new normal situation during the ongoing COVID-19 pandemic is an opportunity as well as a challenge for world tourism in general and Indonesian tourism in particular. The change in lifestyle and habits of the community in traveling directly or indirectly has "hit" this industry very hard. Undeniably, reactivating tourism industry activities do have considerable risk but on the other hand many sectors depend on this industry. Cleanliness, Health, Safety Environment Sustainability (CHSE) strategy conducted by the Indonesian government is one of the efforts in re-mobilizing Indonesia's tourism sector amid the COVID-19 pandemic as well as the opportunity to apply three main principles of sustainable tourism in the new normal era namely involving the social sector in policy engagement maintaining the sustainability of natural resources and making sustainable development a synonym of economic growth.

Dampak pandemi COVID-19 terhadap proses pembelajaran online di SDN Cabean 3 Demak

This study aims to: 1) identify the implementation of online learning at SDN Cabean 3 Demak during the COVID-19 pandemic, 2) identify the impact that occurs in online learning on teachers, students, and parents at SDN Cabean 3 during the COVID-19 pandemic era. 19, and 3) identify the reasons for this impact that could occur in online learning for teachers, students and parents at SDN Cabean 3 during the COVID-19 pandemic. This research is qualitative research with a case study method approach. Respondents in this study were teachers, students, and parents of grade 1 to grade V SDN Cabean 3. Collecting data using open questionnaires, interviews, and documents. Data analysis in this study used a qualitative descriptive analysis with the stages of data reduction, data display, and conclusion drawing / verification. The results showed that, 1) the implementation of online learning at SDN Cabean 3 during the COVID-19 pandemic had been implemented. 2) the implementation of online learning, each class creates a WA group, the teacher, 3) the positive impact in online learning is getting new experiences from online learning, increasing the ability to technology, and more flexible time, 4) While the negative impact is related to the constraints experienced, among others, additional internet quota costs, internet network disruptions, limited mastery of technology, completeness of subject matter not according to curriculum achievements. Keywords: Online learning, critical thinking skills Penelitian ini bertujuan untuk: 1) mengidentifikasi pelaksanaan pembelajaran online di SDN Cabean 3 Demak pada masa pandemi COVID-19, 2) mengidentifikasi dampak yang terjadi dalam pembelajaran online terhadap guru, siswa, dan orang tua di SDN Cabean 3 dalam pada masa pandemi COVID-19, dan 3) mengidentifikasi alasan dampak tersebut dapat terjadi dalam pembelajaran online terhadap guru, siswa, dan orang tua di SDN Cabean 3 dalam pada masa pandemi COVID-19. Penelitian ini merupakan penelitian kualitatif dengan pendekatan metode studi kasus. Responden dalam penelitian ini adalah guru, siswa, dan orang tua siswa kelas 1 sampai dengan kelas V SDN Cabean 3. Pengumpulan data menggunakan kuesioner terbuka, wawancara, dan dokumen. Analisis data dalam penelitian ini menggunakan analisis deskriptif kualitatif dengan tahapan data reduction, data display, dan conclusion drawing/verification. Hasil penelitian diperoleh bahwa, 1) pelaksanaan pembelajaran online di SDN Cabean 3 pada masa pandemi COVID-19 telah dilaksanakan. 2) pelaksanaan pembelajaran online, masing-masing kelas membuat grup WA, guru, 3) dampak positif dalam pembelajaran online adalah mendapatkan pengalaman baru dari pembelajaran online, kemampuan terhadap teknologi meningkat, dan waktu yang lebih fleksibel, 4) Sedangkan dampak negatif terkait kendala yang dialami antara lain, penambahan biaya kuota internet, gangguan jaringan internet, keterbatasan penguasaan teknologi, ketuntasan materi pelajaran tidak sesuai capaian kurikulum. Kata Kunci: Pembelajaran online, kemampuan berpikir kritis

A comparison of perceptions and adapted behaviors between employees and entrepreneurs against pandemic COVID-19 pandemic

New normal is a change in behavior to continue carrying out normal activities and implementing health protocols to prevent COVID-19 transmission. After the implementation of the new normal it automatically affects the routine activities carried out by the community, especially those activities which are limited by the government when the new normal is implemented. This study analyzes perceptions and adaptive behavior between employees and entrepreneurs when implementing new normal during the COVID-19 pandemic. The approach used is a modified Theory of Planned Behavior (TPB). A total of 427 respondents who are employees have answered the online questionnaire containing 61 questions. In this research after the respondent’s characteristics were classified the descriptive analysis carried out with a standard deviation approach mean value and an independent sample T-test were done using the SPSS 25 software. Insignificance was found in indicators of vulnerability and understanding of COVID-19. Significant differences between employees and entrepreneurs were found in the attitude indicators of COVID-19 which are easy to spread the number of cases died the influence of friends the ability to have internet quotas past work behavior past handwashing behavior The perceived severity is related to medical costs if exposed to COVID-19 and reduced income due to the severity of COVID-19. Perceptions between employees and entrepreneurs have significant differences on several indicators. These differences arise because of their environment both the work environment and the environment around where they live. Keywords: COVID-19, adapted behavior, new normal, the theory of planned behavior, employee entrepreneur

COVID-19 and chronic kidney disease: Literature review

COVID-19 virus causes a burden around the world. Quarantine regulations and health protocols affect patients undergoing dialysis therapy every week. COVID-19 is a challenge for nurses in preventing the spread of the virus while providing hemodialysis therapy to patients. The purpose of this review was to formulate and recommend practices for nurses related to services provided to chronic kidney failure patients undergoing hemodialysis. The search method for relevant articles used the database of PubMed, ScienceDirect, and Google Scholar with keywords of COVID-19 + Recommendation + Prevention + Chronic kidney disease + maintenance dialysis + Nursing interventions. Literature search was done from 2020 to 1 March 2021 obtaining 479 research articles. Literature analysis was done by using PRISMA guidelines while the feasibility assessments were applied using JBI Critical appraisal. Eleven articles were included in the literature review. This study found that improving hemodialysis service facilities, health team knowledge, patient education, and policies can be carried out in preventing the spread of COVID-19. The management of patients with dialysis must be carried out according to strict protocols to minimize the risk for other patients. Measures on the prevention, protection, and isolation have been shown to be efficient. Hence it can be summed up that improving health services and patient knowledge are needed to prevent the COVID-19 spread. However, future studies are required to improve evidence-based research of COVID-19 and patient maintenance using hemodialysis therapy. Keywords: Chronic kidney disease;COVID-19;dialysis facilities

Edukasi penerapan protokol kesehatan pada anak jalanan Akur Kurnia Kramat Jati Jakarta Timur

Anak jalanan belum sepenuhnya memahami mengenai pentingnya personal hygiene meskipun ada pemberian beberapa informasi dari volunteer save street child, namun pelaksanaan dalam kehidupan sehari-hari belum diterapkan sepenuhnya hal tersebut ditunjukan dengan sikap acuh tak acuh anak jalanan dalam menjaga personal hygiene. Berdasarkan hasil kajian tersebut maka anak jalanan memiliki peluang yang besar terinfeksi virus Corona dan media penyebaran virus Corona. Kegiatan yang digunakan dalam program pengabdian masyarakat ini berupa penyuluhan edukasi protokol kesehatan dan demonstrasi cara mencuci tangan cara menjaga jarak cara menggunakan masker dan etika batuk. Anak-anak jalanan yang mengikuti penyuluhan dan demonstrasi memahami tentang pentingnya penerapan protokol kesehatan selama masa pandemi dan mampu mendemonstrasikan ulang. Kegiatan ini mampu meningkatkan pengetahuan dan pemahaman tentang pentingnya penerapan protokol kesehatan di masa pandemi COVID-19 sehingga dapat diaplikasikan dalam kehidupan sehari-hari. Kata Kunci: Penerapan Protokol Kesehatan Street children do not fully understand the importance of personal hygiene even though there is several information from volunteers who save street children, but the implementation in daily life has not been fully implemented. This is shown by the indifference of street children in maintaining personal hygiene. Based on the results of this study, street children have a great chance of being infected with the Coronavirus and the media for spreading the Coronavirus. Activities that have been used in this community service program include education on health protocols and demonstrations on how to wash hands, how to maintain distance, how to use masks and cough etiquette. Street children who have attended outreach and demonstrations understand the importance of implementing health protocols during the pandemic and are able to demonstrate again. This activity has been carried out to increase knowledge and understanding of the importance of implementing health protocols during the COVID-19 pandemic so that it can be applied in everyday life. Keywords: Implementation of Health Protocols.